Porto, unbeaten since October, travel to last season's semi-finalists – here's all you need to know.
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Who's likely to start, who might be left out and who is unavailable? UEFA.com predicts all this week's line-ups.
It's the first legs of the round of 16, and #UCLfantasy picks out which players can help you steal a march on your rivals.
The Scout is looking to capitalise on both an enhanced budget and four matchdays to utilise the squad to its full extent.
UEFA's chief refereeing officer Roberto Rosetti has led the project for the introduction of VAR in the UEFA Champions League. Here's his take on how it will be implemented.
Following a decision taken by the UEFA Executive Committee in December 2018, Video Assistant Referees (VAR) will be used in the UEFA Champions League from the round of 16 this season.
With Japan celebrating its national day, which players top the nation's UEFA Champions League rankings?
As the knockout stage kicks off, you have four opportunities to pick the right captain, so maximise your chances.
Ole Gunnar Solskjær hopes his side can "rediscover the Manchester United way" against Paris on Tuesday.
Cengiz Ünder talks about his first 18 months at Roma, the language barrier and making it in the UEFA Champions League.
As the UEFA Champions League round of 16 approaches, The Scout casts his eye over some January additions.