Sevilla have done well to keep Messi, one goal away from a landmark 700 in his career, fairly quiet so far. Barca boss Setien may be tempted to tweak things at the interval, with the likes of Griezmann, Arthur and Fati options to come off the bench.
An ill-tempered first half comes to an end with the sides goalless. Messi tested Vaclik from a couple of free-kicks and Suarez also came close to scoring, but Barcelona did not do enough to warrant a lead against a Sevilla side that improved as the half went on.
45' + 5' HALF-TIME: SEVILLA 0-0 BARCELONA
45' + 5' After all that pushing and shoving, Messi's floated free-kick is cleared and the referee blows for half-time.
45' + 2' There is a flashpoint right at the end of the first half. Carlos goes in hard on Suarez and Messi is not happy with the challenge on his team-mate. He shoves Carlos in the chest and the Sevilla defender theatrically throws himself to the floor.
45' + 2' De Jong chases down Kounde's long pass after getting between Alba and Lenglet. He is unable to get a shot away, however, and the offside flag eventually goes up.
45' + 1' Three minutes have been added on at the end of a so-far goalless first half at the Estadio Ramon Sanchez-Pizjuan.
45' Messi jinks past one man and it looks as though he is about to go on one of those mazy runs of his. However, Fernando stands his ground and Messi runs into a brick wall.
43' Reguilon pulls the ball back for Torres, whose cross into the middle is easily dealt with. It has been a pretty balanced first half on the whole as we approach the interval.
41' Setien's side have not got going at all since the cooling break. Despite being on top, though, Sevilla are not really asking any questions of Barca's defenders.
38' Ocampos swings in a cross from the left and Lenglet gets his head to it first. The Argentina winger has switched flanks since the water break and is far more involved in the match.
37' The hosts wins a couple of corners, the second of which is calmly chested clear by Suarez at the near post. Sevilla are enjoying a rare spell on top, but have still yet to create anything of note.
35' Rakitic is shoved in the back by Fernando just inside the opposition box, but the referee waves away the weak penalty shout.
33' Sevilla are struggling to get Ocampos, their most dangerous player, involved in the match. He has managed just eight touches in the first half.
32' Play resumes following a two-minute stoppage for both sets of players to take on some fluids. Barca have been the better side so far, but they dropped off a bit in the minutes leading up to the cooling break.
30' Barcelona have had 70 per cent of the ball in the opening half an hour. With a third of the match played, the referee calls for the first cooling break.
28' Lenglet gives the ball away high up the pitch. De Jong gets away from the Barcelona defender and skips another challenge, but his attempted through-ball is deflected into the path of Ter Stegen.
26' Rakitic drives the ball towards the bottom-left corner from range, missing the target by a yard or two. This is Barca's best spell of the game.
25' Messi has Vidal to his right and Braithwaite to his left. He decides to go it alone and is dispossessed.
24' MESSI AGAIN! A second free-kick in the space of two minutes from Messi. This latest attempt is also on target, but there is a lot of distance between him and Vaclik, and he is unable to get the better of the Sevilla keeper.
22' MESSI COMES CLOSE! Munir backs into Messi and Barcelona have a free-kick 20 yards from goal - perfect range for Messi. He lifts the ball over the wall and Kounde is well placed to head it off the line. Vaclik probably would have made the save had Kounde not been there, anyway.
20' Reguilon gets high up the pitch pretty much for the first time today. Semedo sticks with him and does well to win the ball without giving away a free-kick, even if the Sevilla full-back felt contact was made.
18' Barca forward Messi drops deep to collect the ball. He spreads it to Vidal and the visitors have players forward, but Rakitic elects to dummy a pass and Sevilla turn over possession.
16' Messi lifts the ball over Sevilla's defence and Alba gets on the end of it, but his first-time cross from the left is dealt with by Kounde.
15' Fernando was brought back into the side today and his task is almost exclusively to man mark Messi. He has not done too bad a job so far, with the Barcelona forward - one goal away from a milestone 700 - seeing little of the ball.
13' CLOSE! Rakitic heads an out-swinging Sevilla free-kick as far as Kounde 15 yards from goal. The defender rather scuffs the shot and it ends inches wide of the far post, with Ter Stegen at full stretch.
11' Sevilla look to get bodies forward quickly but Ocampos kicks the ball straight out of play - a terrible pass, that!
10' Messi and Suarez exchange passes in the opposition box for the first time today. Sevilla stand firm and another promising Barca attack comes to nothing.
9' Barcelona forward Lionel Messi has scored 699 first-team goals in all competitions for club and country, netting 629 for Barcelona and 70 for Argentina. He has scored more goals against Sevilla (37) than any other side in all competitions.
7' Lenglet gets his head to a dangerous cross. That sparks a counter that comes to a disappointing end as Vidal's weak pass towards Suarez is cut out 20 yards from goal.
6' Barca have not taken long to find their rhythm. The visitors are patiently probing away in search of an early breakthrough goal in what is the toughest of their remaining matches.
4' SUAREZ SHOT! Semedo keeps the ball in play down the right and pulls it back to Suarez. The Barcelona striker works the shooting angle and curls one goalwards, but it is very central and Vaclik makes a routine save.
2' Sevilla are pressing their opponents high up the pitch early on. Ter Stegen is caught out and Navas tries to capitalise on a sloppy pass out, but his shot is blocked on the edge of the box.
1' KICK-OFF! Barcelona, aiming to extend their lead at the LaLiga summit to five points, get us up and running!
The teams are coming out onto the pitch at the Estadio Ramon Sanchez-Pizjuan, with kick-off just moments away. This match will be played behind closed doors, as will every other LaLiga game for the foreseeable future.
Sevilla have lost seven of their last eight games against Barcelona in LaLiga, with the other match in that run finishing in a draw. Indeed, today's hosts have suffered more league losses to Barca than they have against any other side in their history (83 defeats in 151 games).
Barcelona show five changes from their midweek win over Leganes, including a couple of tweaks up top. Griezmann and Fati drop to the bench, with their places taken by Braithwaite and Suarez, the latter making his first start since January. Alba is preferred to Firpo after returning from suspension, while Semedo and Vidal are in for Sergi Roberto and Arthur.
Lopetegui has made three changes to Sevilla's starting line-up following their draw with Levante four days ago. Two of those alterations come in central midfield, where Torres and Fernando are recalled in place of Gudelj and Banega, while Escudero is replaced by Reguilon at left-back.
Subs: Chumi, Neto, Junior Firpo, Inaki Pena, Monchu, Ansu Fati, Riqui Puig, Kike Saverio, Arthur, Alex Collado, Antoine Griezmann, Ronald Araujo.
BARCELONA XI (4-3-3): Marc-Andre ter Stegen; Nelson Semedo, Gerard Pique, Clement Lenglet, Jordi Alba; Arturo Vidal, Sergio Busquets, Ivan Rakitic; Lionel Messi (c), Luis Suarez, Martin Braithwaite.
Subs: Rony Lopes, Youssef En-Nesyri, Yassine Bounou, Ever Banega, Jose Mena, Sergio Escudero, Franco Vazquez, Suso, Genaro Rodriguez, Sergi Gomez, Nemanja Gudelj, Pablo Perez.
SEVILLA XI (4-3-3): Tomas Vaclik; Jesus Navas (c), Jules Kounde, Diego Carlos, Sergio Reguilon; Joan Jordan, Fernando, Oliver Torres; Lucas Ocampos, Luuk de Jong, Munir El Haddadi.
Sevilla are third in the table after an impressive campaign to date, two points clear of Atletico Madrid in fourth and a further two ahead of the chasing pack. Julen Lopetegui's side beat rivals Real Betis 2-0 in their first game back last week, but they were denied by a late own goal in Monday's 1-1 draw with Levante
LaLiga leaders Barcelona have won back-to-back matches since returning to action last weekend, following up a 4-0 win at Real Mallorca with a 2-0 victory against Leganes in midweek. Second-place Real Madrid beat Valencia 3-0 on Thursday, but Barca still have a two-point lead at the top with nine games to go.
Hello and welcome to our live coverage of the LaLiga clash between Sevilla and Barcelona at the Estadio Ramon Sanchez-Pizjuan.