That's all for today's live coverage. Thanks for joining!
Guardiola's side have closed the gap on leaders Liverpool to 22 points with nine games remaining. Next up for City is a home match against Burnley on Monday, while Arsenal - five points off the top five - travel to Brighton and Hove Albion on Saturday.
Man City mark their return to Premier League action with a comfortable 3-0 win over 10-man Arsenal. David Luiz's error gifted Sterling the opening goal late in the first half and the centre-back, brought on for the injured Mari, then saw red for giving away a penalty that De Bruyne converted. Foden added a third in stoppage time after fellow substitute Aguero's shot had come back off the post.
90' + 11' FULL-TIME: MANCHESTER CITY 3-0 ARSENAL
90' + 9' Manchester City midfielder Phil Foden has more goal involvements this season in all competitions - four goals and seven assists - than his previous two campaigns (10).
90' + 7' SIDE-NETTING! Foden plays the ball into the feet of Aguero and the striker has only Leno to beat. He takes the shot slightly early and slices it somewhat, only managing to pick out the side-netting.
90' + 6' WIDE! Bernardo skews a shot wide of the target after being picked out by Gundogan, who has had a good game today.
90' + 5' The hosts are knocking the ball around with the swagger of a side three goals to the good. They look as though they have a fourth goal in them before the end of the game.
90' + 3' There was an impressive deep pass from Fernandinho in the build-up to that third City goal, showing just why Guardiola is so keen to use him at centre-back. If Arsenal were not already out of the contest, they certainly are now.
90' + 1' Eleven minutes have been added on at the end of the game.
89' CITY DOWN TO 10 MEN! Garcia is taken down the tunnel on a stretcher - fingers crossed he is okay after that nasty collision with Ederson. Guardiola has already used all five substitutions, so it is 10 against 10 for the remainder of the game.
88' City defender Garcia is still being treated on the field - the physios understandably cannot take any risks given it is a head injury. There could well be more than 10 minutes added on here when factoring in all the subs.
86' There are some worried looks on the faces of City's players after seeing one of their team-mates possibly knocked unconscious. This injury has taken up about six minutes now, which will no doubt be added on at the end.
84' Garcia may well have been knocked out by Ederson. The physios will take all the time they need to ensure the young defender is safely placed on the stretcher.
82' Ederson races out of his box and, in an attempt to win the ball, takes out team-mate Garcia. It looks a nasty one, with Ederson seemingly catching Garcia in the face. The City physios are on the pitch and the stretcher is also brought on.
78' NEARLY A THIRD! Sterling catches out the opposition by passing the free-kick to Gundogan, rather than taking on the shot as expected. Gundogan is unable to beat Leno, though, with the Arsenal keeper - undoubtedly their best player today - making a low save.
74' Play picks up from where it left off before the water break as City continue to pass the ball around Arsenal. It has been far too easy for the hosts ever since they opened the scoring late in the first half.
73' It is time for another water break at the Etihad Stadium. Arteta and Guardiola have a chance to speak to their players.
71' There is absolutely no pressure on the ball now from City's perspective as they continue to play it around Arsenal. The 10-man visitors seem happy to settle for just a two-goal defeat.
69' SAVE! De Bruyne makes a smart run into the box and is spotted by Sterling. His drilled shot is kept out by Leno in a fairly routine manner.
64' Arsenal are not out of this game yet given there are only two goals in it, but they are offering absolutely nothing at the moment. City are cruising through the match, with their latest attacking move culminating in Leno getting down to cut out a cross.
62' City's players are simply knocking the ball around between them now. Arteta is holding off from making his third change for the time being.
61' Arsenal defender David Luiz has conceded four penalties in the Premier League this season, double the amount of any other player.
60' SHOT! Guendouzi does not close down Jesus quickly enough and the City striker takes range from 25 yards. The shot is central and Leno has a straightforward save to make.
58' David Luiz is the first player to be sent-off, concede a penalty and commit an error leading to an opposition goal in a Premier League match since Carl Jenkinson for West Ham v Bournemouth in August 2015.
56' Tierney cuts out Mahrez's right-sided cross before Jesus can pounce. Guardiola may well be tempted to make a change or two of his own as we approach the hour mark in Manchester.
54' Arteta is trying to work out what to do next. Mustafi is limping along following that challenge from Sterling, so a bad day may be about to get even worse for the visitors.
53' Sterling lunges in on Mustafi with a scissor-type challenge. Arsenal's players want the City forward sent off, but the referee does not even reach into his pocket.
49' PENALTY TO MAN CITY! Mahrez chests down the ball and gets the wrong side of Luiz. The Arsenal centre-back brings down his opponent inside the box and the hosts have a penalty.
49' Arsenal hit City on the counter. Saka plays it down the line to Willock, but his back-heeled pass inside the box does not come off.
48' Ederson goes long and Mahrez looks to be in, only for a bad first touch to let him down and Leno to gather.
47' The home side are in no rush to get the ball forward in the early stages of the second half. Arsenal are unable to get their foot on it at the moment.
46' RESTART! Man City, leading 1-0 thanks to Sterling's strike, get us back up and running at the Etihad Stadium. Neither coach made any changes at the interval, so it is as you were.
Arsenal lost Xhaka and Mari to injury in the opening 24 minutes of the match, but Arteta still has three substitutions available and may well choose to use one at the break. Pepe, Lacazette and Martinelli are all among the visitors' subs, while City can call upon the likes of Aguero, Sane and Bernardo.
City take a 1-0 lead into half-time thanks to Sterling's strike right at the end of the first half, with the England international profiting from some terrible David Luiz defending. It is a deserved advantage for Guardiola's men, having tested opposition goalkeeper Leno five times before Sterling's breakthrough goal.
45' + 4' HALF-TIME: MANCHESTER CITY 1-0 ARSENAL
45' + 3' Raheem Sterling has been directly involved in six goals in his last seven Premier League appearances for Manchester City against Arsenal (four goals and two assists).
45' Three minutes have been added on at the end of the so-far goalless first half at the Etihad Stadium.
44' Walker backs into Tierney and Arsenal have a rare chance to test City from a deep free-kick. Saka's delivery is brilliant, but it drops just in front of Mustafi and the centre-back fails to make any contact.
42' Arteta could do with half-time because City are knocking on the door for a breakthrough goal. If not for Leno's heroics, the reigning champions would be a goal or two ahead as we approach the interval.
40' CHANCE FOR STERLING! Arsenal are seriously holding on now. De Bruyne plays a simple pass through for Sterling, who attempts to dink the ball over Leno with just the goalkeeper to beat. He gets too much on it and the ball spins over the crossbar.
38' LENO DENIES MAHREZ! Leno is keeping Arsenal in this game. He makes a third save in pretty much the same number of minutes, this time denying Mahrez from close range after the winger was played in by De Bruyne.
37' That was a well-worked move from City. They are now bossing things in terms of possession and are starting to create some good opportunities.
36' ANOTHER LENO STOP! City are definitely growing more and more into this game. Silva gets in behind the Arsenal defence and fires a low shot across goal, which Leno is again equal to. Ceballos is first to the loose ball.
35' GOOD SAVE! Sterling cuts inside Bellerin and bends a shot towards the bottom-right corner. Leno does well to get down and push the ball behind for a corner - that is as close as City have come today.
34' Garcia is all over Nketiah as he sends his opponent crashing to the ground just outside the City box, but the referee Anthony Taylor waves play on.
33' City are slowly starting to find their groove. De Bruyne exchanges passes with Gundogan 25 yards from goal and pulls the trigger, though his shot is blocked by an Arsenal player.
31' David Luiz intercepts the ball and plays it to Ceballos, who drifts into a central position from the left. A cross eventually comes in from the right but Walker is able to chest it back to Ederson.
30' Arsenal are unbeaten in their last seven away league games, with each of their last five in a row ending level. The north London club have never drawn six consecutive away league games.
28' De Bruyne turns down the chance to shoot from the edge of the box and instead attempts to slip in Mahrez. The Algeria winger cannot bring it under control, however, and a promising attack for City fizzles out.
26' Saka's early cross from the right is aimed too close to Ederson. De Bruyne gives away possession as City attempt to play it out from the back, but Aubameyang's shot from the edge of the box is off target.
24' Experienced centre-back David Luiz is stripping down ready to come on. It is a second injury blow for Arteta with less than a quarter of the game played.
23' Walker powers away from Mari down the right-hand side and cuts the ball back, but nobody in a sky blue shirt can get on the end of it. Worryingly for Arteta, Mari pulled up with a possible calf injury.
22' City are patiently probing away, with Arsenal dropping off - perhaps a tad too deep. Bellerin gets to the ball ahead of Walker down the left, but any hope of a quick break is thwarted by Garcia.
20' With 20 minutes played, possession is split exactly down the middle. There has been very little between the teams so far, with both sides still trying to feel their way into the contest.
18' Walker gets across to cut out a cross at the expense of a corner. The set-piece is headed away by Jesus at the front post.
17' Nketiah has looked very sharp in the opening 17 minutes or so. The former Leeds United loanee has got in behind Garcia a couple of times - City cannot afford to give him too many sights of goal.
15' WIDE! Saka sends in a cross towards Nketiah. The Arsenal striker gets in front of a wrong-footed Garcia but is unable to direct the ball on target.
14' It is very compact in midfield at the moment. Arsenal are enjoying a spell on the ball but - like City - are not doing a lot with it, other than recycling it between their defenders and midfielders.
12' City are seeing plenty of the ball at the moment, without doing a great deal with it. Jesus tries to chase down a pass in behind but it has too much on it and goes out for a goal-kick.
10' City win another corner, which De Bruyne swings towards the six-yard box. Mari heads it as far as Mahrez, whose shot takes a touch on its way behind for a goal-kick.
7' It does not look good for Xhaka. The stretcher is now on the field, so it is fair to say his match - and possibly even his season - is over just seven minutes into the restart.
6' Xhaka collides with team-mate Guendouzi and is in need of some treatment. The Arsenal midfielder appears to have injured his right ankle and may well have to make way early on.
4' SAVE! De Bruyne whips the free-kick around the wall. Leno watches it all the way and palms the ball over the crossbar.
3' Mari catches Sterling when attempting to clear the ball a yard or so outside his own penalty area. City have a free-kick in shooting range, with De Bruyne one of two players stood over the ball...
2' Nketiah gets between City's two centre-backs and chases down Leno's long pass. He is through on goal, but his shot is pretty terrible and the offside would have denied him anyway.
1' As was the case in the Aston Villa versus Sheffield United match a little earlier, every Man City and Arsenal player took a knee in support of the Black Lives Matter movement before the first ball was kicked.
1' KICK-OFF! Following a minute's silence to remember all those who have lost their lives to coronavirus, Arsenal get us underway at the Etihad Stadium.
The teams are coming out onto the pitch at the Etihad Stadium, with kick-off just moments away. This match will be played behind closed doors, as will every other Premier League game between now and the end of the season.
Manchester City have won their last six matches against Arsenal in all competitions - their best-ever run against the Londoners - with five of those victories coming in the Premier League.
Arsenal show five changes from their slender win over West Ham in early March. The big news is that Mesut Ozil is left out of the matchday squad, despite Arteta confirming pre-match that the German midfielder is not injured. Sokratis also misses out entirely, while Pepe, Ceballos and David Luiz drop down to the bench. Bellerin, Mustafi, Guendouzi, Willock and Saka are all recalled to a youthful XI.
Guardiola has made eight changes to City's starting line-up following their Manchester derby defeat a little over three months ago. Gundogan, Sterling and Ederson, who will make his 100th Premier League appearance, are the only three players to retain their place in the side. Elsewhere, Jesus is selected over Aguero up top, Garcia starts in defence and Sane is named in the matchday squad for the first time in 10 months.
Subs: Alexandre Lacazette, Nicolas Pepe, David Luiz, Sead Kolasinac, Emiliano Martinez, Reiss Nelson, Ainsley Maitland-Niles, Dani Ceballos, Gabriel Martinelli.
ARSENAL XI (4-2-3-1): Bernd Leno; Hector Bellerin, Pablo Mari, Shkodran Mustafi, Kieran Tierney; Granit Xhaka, Matteo Guendouzi; Eddie Nketiah, Joe Willock, Bukayo Saka; Pierre-Emerick Aubameyang (c).
Subs: Bernardo Silva, Nicolas Otamendi, Sergio Aguero, Rodrigo, Scott Carson, Fernandinho, Leroy Sane, Phil Foden, Oleksandr Zinchenko.
MAN CITY XI (4-3-3): Ederson; Kyle Walker, Eric Garcia, Aymeric Laporte, Benjamin Mendy; David Silva (c), Ilkay Gundogan, Kevin De Bruyne; Riyad Mahrez, Gabriel Jesus, Raheem Sterling.
Arsenal, managed by former City assistant Mikel Arteta, won three league games in a row before football was brought to a halt in March. Their most recent match on March 7 ended in a 1-0 victory over London rivals West Ham, leaving them ninth in the table and five points adrift of fifth-place Manchester United, who have played a game more.
More than 100 days on from their most recent match, a 2-0 loss to bitter rivals Manchester United, reigning champions City resume their campaign with a tasty home fixture against Arsenal. Pep Guardiola's side lost two of their last four matches before the coronavirus-enforced hiatus and are 25 points adrift of leaders Liverpool with this game in hand to play.
Hello and welcome to our live coverage of the Premier League clash between Manchester City and Arsenal at the Etihad Stadium.