64' Manchester City midfielder Phil Foden has been directly involved in 13 goals in his last 17 appearances in all competitions - five goals of his own and eight assists.
61' De Bruyne curls a shot wide of the target after a nice give-and-go with Mahrez. That came after Firmino and Oxlade-Chamberlain had shots blocked at the other end.
60' City are looking a little sloppy in possession, though it does not really matter when three goals ahead. Liverpool have not really looked like reducing the arrears in the second half.
59' Mahrez is playing through the middle, with support being offered from wide by Sterling and Foden.
58' Alexander-Arnold's whipped free-kick has a little too much on it and ends wide of the target.
57' POSSIBLE LIVERPOOL PENALTY! Walker barges into Mane, who made a positive run in behind. A VAR check confirms the contact - which was minimal to say the least - was made outside the penalty area. It is just a free-kick for the visitors.
55' SHOCKER! Mane is played in by Henderson and has just Ederson to beat - or at least that would have been the case had he not let the ball roll under his feet. Terrible control from the Liverpool forward!
53' Garcia's clearance ricochets off Laporte but thankfully for the City defenders the ball ends right down Ederson's throat.
52' OFF THE LINE! De Bruyne makes a mockery of Liverpool's defensive line and cuts the ball back for Foden, who scuffs a shot past Alisson. Van Dijk gets back to clear the ball off the line.
51' ANOTHER CHANCE! Liverpool are all over the place. Sterling spins in behind, runs a good 25 yards and fires a shot on target. Fabinho puts his body on the line and the deflection sends the ball spinning wide of Alisson's post.
50' BIG CHANCE FOR FOUR! Alexander-Arnold throws the ball straight at Jesus. Fabinho backs off and the City forward charges towards the box, only to shoot right at Alisson from the edge of the box.
49' The second half has not really got going so far. Many may have expected Liverpool to come out all guns blazing, but that has not really been the case.
47' Fabinho has indeed slotted in alongside Van Dijk at centre-back, with Liverpool retaining their same 4-3-3 formation.
46' RESTART! City, leading by three goals following a pretty incredible first half, get us back up and running at the Etihad Stadium.
The visitors actually started the match pretty well and looked lively up top throughout the half, but they let themselves down defensively - it is not often that has been said over the past couple of seasons! Klopp will surely be tempted to make a change or two at the break, with the likes of Milner, Oxlade-Chamberlain and Keita among his subs.
City lead Liverpool, the side that replaced them as champions last week, 3-0 at half-time. De Bruyne opened the scoring from the penalty spot after Gomez brought down Sterling in the box and Sterling added a second 10 minutes later. Foden set that goal up and was on the scoresheet himself before the break after being played in by the impressive De Bruyne.
45' + 4' HALF-TIME: MANCHESTER CITY 3-0 LIVERPOOL
45' + 3' Salah has space on the right-hand side and Mane is waiting for the ball in the middle. The Egypt international overhits the cross and City survive a bit of a scare - if you can go as far as calling it that when three goals ahead!
45' + 2' Klopp will be furious with his side's defending for that third goal in particular. Robertson stepped out of defence and was punished by Foden. He may have got away with it against the 18 other teams in the division, but not City.
43' The game has gone a bit sloppy over the last five minutes or so. Liverpool are bossing possession but City are not really under any threat at the back.
40' Liverpool have spent a couple of minutes knocking the ball around, without any real purpose. A floated pass down the right towards Robertson trickles out of play for a City throw.
38' Klopp will be wondering how his side are two goals down. Liverpool had some promising opportunities with the scoreline level and now find themselves 2-0 behind.
36' That was Raheem Sterling's first goal against Liverpool since leaving the Reds for Manchester City five years ago.
34' Ederson races well off his line, as is now customary, and is caught by Salah. He escapes without any sort of injury, however, and play continues.
33' A flowing Liverpool move culminates in Fabinho's first-time pass being cut out in the centre. Firmino had a chance to play Mane in on goal earlier in the attack.
31' Walker is caught out of position by Mane, who chases down Van Dijk's pass and charges into the box. Garcia loses his footing but Mane is unable to pick out a team-mate.
30' WHAT A PASS! Following some slick passing in midfield, De Bruyne plays yet another incredible through-ball for Jesus. The Brazil forward this time manages to stay onside, but he can only pick out the side-netting with his poor attempt.
28' While Liverpool have arguably been the better team so far, De Bruyne has been the best player on the field. That was a well-taken penalty, too - City's spot-kick woes seem to be a thing of the past.
26' Since the start of 2015-16, only Crystal Palace winger Wilfried Zaha (15) has won more penalties than Manchester City's Raheem Sterling (14) in the Premier League.
24' PENALTY TO CITY!! De Bruyne had a weak penalty shout rejected a couple of minutes ago after being grabbed by Van Dijk. Well City have a penalty now, with Gomez keeping hold of Sterling's shirt for a little too long.
23' In his managerial career, Manchester City boss Pep Guardiola has lost more games against Jurgen Klopp than he has any other manager (eight), while against no side has he lost more games than he has against Liverpool (five, level with Manchester United and Chelsea).
21' OFF THE POST! Salah drifts in from the right and sends a reverse shot across Ederson and back off the post. Mane gets on the end of the loose ball but is unable to bring it under control.
19' De Bruyne, who appears to be over that early knock he sustained, rolls a first-time pass through for Jesus. Once again, however, the Brazil forward is flagged for offside.
17' Foden rather needlessly fouls Robertson to give away a free-kick deep in the Liverpool half. The hosts have had 62 per cent of the ball in the opening 17 minutes.
15' Mendy's delightful cross from the left is missed by Van Dijk and Robertson. Foden is running in at the back post but is also unable to slide it in.
14' The champions are looking the side more likely to score at the moment. A stray pass from Gundogan is just out of Mane's reach, but that is another example of City being unsettled by their opponents' high press.
12' CHANCE! Mane sends a downward header wide of the target from a good position. Team-mate Salah may well have put him off there.
11' This is worrying for City as De Bruyne appears to have hurt his knee in a challenge with Fabinho. He is hobbling around for now but Guardiola will be keeping a close eye on that.
10' There are fireworks being let off around the Etihad Stadium, presumably by Liverpool supporters. On the field, De Bruyne blasts a shot goalwards but it is blocked in front of goal.
8' Guardiola's men have not really settled down, not helped by Liverpool's frantic pressing. A replay of that earlier Jesus offside shows he was an inch offside.
7' Liverpool once again get in behind City's back-line. Alexander-Arnold's pass is overhit, however, and Mane is forced too wide to do anything with it.
5' SAVE! Salah makes a straightforward run through the heart of City's defence and brings Van Dijk's floated pass under control. His shot is parried by Ederson, who recovers by making a second save from Mane's weak follow-up.
3' OFFSIDE! Jesus calmly slots the ball past Alisson but was clearly offside and probably knew the flag was going to go up. A good finish from the Brazil forward, all the same.
2' Liverpool are pressing City high up the pitch right from the off. It pays off as possession is turned over, but Fabinho cannot quite slip the ball through for Mane.
1' KICK-OFF! Liverpool get us up and running in this clash between reigning champions and dethroned champions. The visitors still have a number of records in their sights and will be targeting victory here.
The teams are about to enter the field at the Etihad Stadium. Liverpool's players will be greeted with a guard of honour from their opponents, as is customary for the champions in their remaining league fixtures.
Manchester City have won their last two Premier League home games against Liverpool - not since March 1937 have they won three in a row against the Reds.
Klopp has named an unchanged line-up following Liverpool's 4-0 win over Crystal Palace eight days ago, meaning a midfield three of Henderson, Fabinho and Wijnaldum. Dejan Lovren and Joel Matip miss out on the squad through injury, but Milner is back on the bench against his former club after shaking off a hamstring issue.
City show four changes from Sunday's 2-0 win over Newcastle United in the FA Cup quarter-finals. Garcia and Foden are recalled to the side in place of Otamendi and David Silva, while Mahrez and Bravo are replaced by Rodrigo and Ederson. Academy product Doyle is named in the matchday squad for a league game for the second time this season.
Subs: Divock Origi, Curtis Jones, James Milner, Neco Williams, Takumi Minamino, Adrian, Alex Oxlade-Chamberlain, Harvey Elliott, Naby Keita.
LIVERPOOL XI (4-3-3): Alisson; Trent Alexander-Arnold, Joe Gomez, Virgil van Dijk, Andy Robertson; Jordan Henderson (c), Fabinho, Georginio Wijnaldum; Mohamed Salah, Roberto Firmino, Sadio Mane.
Subs: Nicolas Otamendi, Joao Cancelo, Riyad Mahrez, John Stones, Bernardo Silva, Claudio Bravo, Tommy Doyle, David Silva, Oleksandr Zinchenko.
CITY XI (4-2-3-1): Ederson; Kyle Walker, Eric Garcia, Aymeric Laporte, Benjamin Mendy; Rodrigo, Ilkay Gundogan; Phil Foden, Kevin De Bruyne (c), Raheem Sterling; Gabriel Jesus.
City have won three of their four matches in all competitions since returning to action last month, the exception being that loss at Stamford Bridge. Pep Guardiola's men had won the title in back-to-back campaigns but find themselves well off the pace this time around, trailing champions Liverpool by a whopping 23 points.
Liverpool are in action for the first time since being crowned Premier League champions following Chelsea's victory over City a week ago today. Jurgen Klopp's men, who dethroned City as England's top club, will be given a guard of honour by their opponents ahead of this clash between the top two.
Hello and welcome to our live coverage of the Premier League meeting between Manchester City and Liverpool at the Etihad Stadium.