With Man City 11 points clear at the top of the Premier League table, Chelsea and Liverpool are desperate for three points at Stamford Bridge as they attempt to keep pace in the title race.
It looked as if Arsenal would end their long wait for a league win against Man City, but a short second-half spell turned the game on its head and set up the visitors to win late and move 11 points clear.
Manchester City began 2022 with an 11th consecutive Premier League win, coming from behind to win a fiery encounter 2-1 at Arsenal, who had Gabriel sent off.
Unbeaten in eight Premier League games under Antonio Conte, Spurs will go fifth with a win at Vicarage Road. Watford, meanwhile, are two points above the relegation zone and winless since Nov. 20.
The Premier League begins 2022 with a bang as champions Manchester City, on a run of 12 straight wins, travel to face an Arsenal side who have scored 19 goals in their last five games.