Eighteen-year-old Amad Diallo came off the bench to score his first goal for Manchester United but a late AC Milan equaliser means the Red Devils face an uphill battle in the second leg.
Arsenal are in Athens to take on Olympiakos and Tottenham welcome Dinamo Zagreb to north London as the Europa League round of 16 continues. Follow the action live on ESPN.
Amad Diallo scored his first goal for Manchester United, but the Red Devils were pegged back in the second minute of stoppage time by AC Milan in their Europa League last-16 first leg.