PSV Eindhoven and Tottenham are without a point in Group B and cannot afford a third defeat as they meet.
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Shakhtar Donetsk are aiming for a repeat of last season's win against Manchester City in Ukraine.
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Borussia Dortmund and Atlético Madrid are level on six points at the top of Group A ahead of their meeting in Germany
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Paris Saint-Germain and Napoli are both in high spirits having picked up morale-boosting Group C wins last time out.
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A last-gasp matchday two defeat means Liverpool need to draw on their impressive home form again as Crvena zvezda visit.
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Barcelona's last home game with Internazionale ended in a memorable result for the Italian visitors.
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Thierry Henry, 41, has taken his first job as a head coach at Monaco, the club where he began his playing career.
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Robert Lewandowski has brought up a century of Poland appearances; celebrate his genius with UEFA.com.
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Former Bayern keeper Oliver Kahn is the latest UEFA Champions League centurion in the spotlight.
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Robert Lewandowski is set to bring up a century of Poland appearances; celebrate his genius with UEFA.com.
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