Despite dominating large parts of the first half, Arsenal do not have much to show for their efforts as the sides go in 0-0 at half-time. Arteta's men did create half chances through both Willian and Saka, however, down the other end United will argue that Greenwood easily could have opened the scoring for them.
45' HALF-TIME: MANCHESTER UNITED 0-0 ARSENAL
44' CHANCE! Saka has a free header as he gets on the end of Bellerin's right-footed cross near the penalty spot but heads just over the bar. Willian had initially done well down the left to create the room for Bellerin's cross that found Saka.
43' Rashford has the Arsenal defence concerned as he chests down a loose ball and looks to shoot. Dean has different ideas as he insists that Rashford has handled it and awards the visitors a free-kick inside their own area.
42' The visitors again invite United to press them high up the pitch and play through them, however, this time Saka can't get the final vital touch to slide in Willian as they break over the halfway line.
41' Bellerin does well to find Willian out wide on the right-hand side but the Brazillian wastes the chance as he looks to cross deep to Saka and sends it out of play for a goal-kick.
39' OFF THE BAR! Willian and Aubameyang exchange passes on the edge of the area, with the latter flicking a pass towards Willian, who curls a left-footed shot towards the far post. De Gea doesn't move but the Brazillian's shot falls the wrong side of the bar as it clips the top and sails over.
37' Lacazette is teed up by Aubamayeng at the back post, but the French striker manages to fluff his lines as he completely misses the ball when attempting to take his left-footed shot. Replays show that Lindelof got a little touch on the initial pass to throw Lacazette off his mark.
37' Fernandes, Greenwood and Rashford press as a trio but Arsenal are content to play backwards towards Leno and retain possession with just under 10 minutes left in the first half.
35' Lacazette spins past two United midfielders and plays a short pass to Willian, who attempts to chip a ball to Aubameyang at the back post but Lindelof gets a little toe on the pass to deflect it out of play. Dean fails to see the touch and awards United the goal-kick.
34' The visitors play effectively through United's press, however, the move eventually breaks down as Partey is fouled before Arsenal can progress further up the pitch.
33' Saka makes an audacious effort to switch the play to Willian but the pass is well overhit and trickles out for a United throw-in.
32' The Red Devils are winless in their three home league games so far this season (D1 L2), last failing to win any of their first four at Old Trafford in 1972-73. In fact, United are winless in their last five league games at home, their longest such run since February 1990 (6).
30' Aubameyang is lucky to escape a booking as he slides in late through the back of Fernandes to gift United a set-piece 40 yards from goal. The Portuguese midfielder takes it but Arteta's defence deal with the aerial threat and clear down the pitch.
29' Elneny beats three men with a drop of the shoulder and then tries to release Saka but Wan-Bissaka matches the England international for pace and intervenes before Saka can trouble De Gea.
27' Saka and Aubameyang attempt to link-up but the latter fails to flick a pass around the corner and Wan-Bissaka gets the chance to intervene.
24' Wan-Bissaka carelessly gives the ball away and then adds to his woes by fouling Saka near the byline on the left. Willian takes the free-kick but, again, doesn't beat the first United shirt in the area.
21' SAVE! Rashford finds Greenwood at the back post and the youngster drives a left-footed shot towards the near post which Leno is forced to save with his feet.
20' Arteta's side have definitely had the better of the opening 20 minutes, with United rarely getting any decent possession, however, the score remains at 0-0 so the visitors have nothing to show for their good start.
19' Tierney looks to find Aubameyang with a curled pass down the line but Maguire is there to shepherd the ball out for a United goal-kick.
17' Greenwood thinks he is in after Fernandes' pass, but the assistant's flag is up for offside, much to the relief of Tierney and Gabriel.
16' Holding clatters into the back of Rashford's head as the centre-back goes up for an aerial duel and United will have a free-kick inside Arsenal's half.
15' CHANCE! Bellerin reaches the byline and fizzes a right-footed cross across goal towards the back post, all Aubameyang has to do it get a touch for a tap-in but he can't quite reach it to open the scoring.
13' Lacazette gets a bit too carried away and brings Fred down near the centre circle which allows United a bit of respite and the opportunity to knock the ball about round the back as they look to work an opening.
11' Saka carries the ball over halfway before Aubameyang and Partey exchange passes outside the area. Saka eventually finds himself in space on the left of the box but can't manage to drag a cross back in the direction of Lacazette at the back post.
10' The Gunners have won two of their last three top-flight games against the Red Devils (D1), as many as they had in their previous 15 against them (W2 D5 L8). Indeed, Arsenal are unbeaten in their last four league games against their opponents, last having a longer such run against them between 1989-1992 (5 games).
9' Pogba looks to break onto Rashford's throughball but the Frenchman is quite clearly well offside and the assistant rightfully has his flag up on the far side.
8' There is a bit of confusion between De Gea and captain Maguire with the latter heading out for a second Arsenal corner, despite the Spanish goalkeeper being stood behind him waiting to catch Saka's deep cross.
7' The first corner of the game comes on the left-hand side which Willian takes, but he doesn't beat the first man and that is easy for United's defence to deal with.
6' Partey tries to fizz a pass into the feet of Lacazette but his touch is poor and United intercept. However, the hosts can't quite make it out their half as of yet and once again give the ball back to the visitors in the middle of the park.
5' Willian needlessly gives possession away near the centre circle and then drags Fernandes back to stop the counter-attack. The Portuguese midfielder clutches his face and Willian is perhaps lucky to escape a booking for that tactical foul.
3' Willian has two attempts to cross but fails to beat the towering pairing of Maguire and Lindelof, making it easy for the centre-backs to deal with the danger and clear down the pitch.
2' Maguire does well under the pressure of Lacazette to remain calm and retain possession, playing through Arsenal's high press as United work the ball from one side of the pitch to the other in the opening stages.
1' Referee Mike Dean blows his whistle to get this Premier League fixture under way!
The players are making their way out at Old Trafford and shortly the start of the game will be upon us.
This will be the first league meeting between the two sides in which both teams are in the bottom half of the table since October 1936.
Mikel Arteta makes 10 changes from Arsenal’s win over Dundalk, with Elneny the only man present in both line-ups. It also looks more like a back four here, as opposed to the usual three-man defence that Arteta often opts for.
Despite performing well in midweek, there is still no room for Donny van de Beek in United's Premier League starting XI. Rashford, after grabbing a 18-minute hat-trick against Leipzig, starts up top with Greenwood, while McTominay comes in in midfield.
SUBS: Nicolas Pepe, Ainsley Maitland-Niles, Runar Alex Runarsson, Granit Xhaka, Shkodran Mustafi, Eddie Nketiah, Dani Ceballos.
ARSENAL (4-3-3): Bernd Leno; Hector Bellerin, Gabriel Magalhaes, Rob Holding, Kieran Tierney; Thomas Partey, Mohamed Elneny, Bukayo Saka; Alexandre Lacazette, Willian, Pierre-Emerick Aubameyang.
SUBS: Juan Mata, Nemanja Matic, Axel Tuanzebe, Donny van de Beek, Dean Henderson, Brandon Williams, Edison Cavani.
MANCHESTER UNITED (4-3-1-2): David de Gea; Aaron Wan-Bissaka, Victor Lindelof, Harry Maguire, Luke Shaw; Fred, Paul Pogba, Scott McTominay; Bruno Fernandes; Marcus Rashford, Mason Greenwood.
Both teams come into this game after emphatic midweek victories in Europe over RB Leipzig and Dundalk respectively. Prior to that, in the league the hosts endured a stalemate against Chelsea, while the Gunners were defeated by Leicester City.
Hello and welcome to live coverage of the Premier League fixture between Manchester United and Arsenal at Old Trafford.