Subs: Alisson, Rodrigo Caio, Everton Ribeiro, Weverton, Emerson, Fabinho, Renan Lodi, Lucas Paqueta, Vinicius Junior, Everton, Gabriel Barbosa, Felipe.
BRAZIL (4-2-2-2): Ederson; Danilo, Eder Militao, Marquinhos, Alex Sandro; Casemiro, Fred; Gabriel Jesus, Richarlison; Roberto Firmino, Neymar.
Subs: Fabian Balbuena, Robert Piris Da Motta, Alejandro Romero Gamarra, Gabriel Avalos, Alfredo Aguilar, Alberto Espinola, Andres Cubas, David Martinez, Braian Samudio, Antonio Bareiro, Oscar Romero, Gerardo Ortiz.
PARAGUAY (5-3-2): Antony Silva; Robert Rojas, Gustavo Gomez, Junior Alonso, Omar Alderete, Santiago Arzamendia; Mathias Villasanti, Gaston Gimenez, Angel Cardozo; Miguel Almiron, Angel Romero.
It's three changes for the visitors, with Ederson handed the gloves and Gabriel Jesus and Roberto Firmono both drafted into the starting XI. The hosts make a pair of swaps: Junior Alonso and Santiago Arzamendia get the nod to begin from the off.
Paraguay - quarter-finalists at South Africa 2010 a decade ago, of course - are looking to book their first return since this time around, having missed out on Brazil 2014 and Russia 2018. A surprise victory here could vault them into the top four and keep them firmly on the front foot.
The rescheduled tournament, shifted from Argentina and Colombia to the Selecao's own backyard, has attracted widespread criticism from its players, with talks of a boycott. But all their focus today will surely be on ensuring they head back with another three points.
Having swatted aside Ecuador on home soil last week, Tite's side make the trip across the continent now with a view to further strengthening their spot at the head of the race for next year's tournament - and possibly to fine-tune ahead of a controversial Copa America.
Hello and welcome to live coverage of the CONMEBOL Qatar 2022 World Cup qualifiers as Brazil look to keep their spotless record intact against fellow hopefuls Paraguay at Estadio Defensores del Chaco in Asuncion.