Spezia have lost two of their last four home Serie A games (W1 D1), having avoided defeat in their previous six before this run (W3 D3).
Juventus manager Massimiliano Allegri, however, makes sweeping changes after the 1-1 draw with Milan on Sunday. Alex Sandro, Locatelli, Cuadrado and Morata are dropped to the bench, while Giorgio Chiellini misses out altogether. De Ligt, De Sciglio, McKennie, Chiesa and Kean all come into the side.
Spezia boss Thiago Motta makes two changes to the team that beat Venezia 2-1 last time out. Bourabia keeps his place in midfield after scoring the winning goal deep into stoppage time last weekend, with Sala dropping to the bench. Defender Martin Erlic was forced off with an injury in that game and replaced by Hristov, who keeps his spot and starts this evening.
Juventus substitutes: Mattia Perin, Juan Cuadrado, Alex Sandro, Carlo Pinsoglio, Aaron Ramsey, Dejan Kulusevski, Luca Pellegrini, Alvaro Morata, Manuel Locatelli, Federico Bernardeschi, Daniele Rugani.
Juventus (4-3-3): Wojciech Szczesny; Danilo, Matthijs de Ligt, Leonardo Bonucci, Mattia De Sciglio; Weston McKennie, Adrien Rabiot, Rodrigo Bentancur; Paulo Dybala, Moise Kean, Federico Chiesa;
Spezia substitutes: Ivan Provedel, Petar Zovko, Eddie Salcedo, Jakub Kiwior, M'Bala Nzola, David Strelec, Suf Podgoreanu, Rey Manaj, Nicolo Bertola, Jacopo Sala.
Spezia (4-3-3): Jeroen Zoet; Kelvin Amian, Petko Hristov, Dimitris Nikolaou, Simone Bastoni; Salvador Ferrer, Mehdi Bourabia, Giulio Maggiore; Daniele Verde, Janis Antiste, Emmanuel Gyasi.
Struggling Juventus come into this game in the relegation zone and still searching for their first league win of the season. To do so, they must overcome a Spezia side that collected their first victory of the campaign on Sunday, beating newly-promoted Venezia.
Hello and welcome to our LIVE coverage of the Serie A fixture between Spezia and Juventus at Stadio Alberto Picco.