The Super Eagles striker helped Gennaro Gattuso's men grab their third straight win win away from home in the Italian top-flight
Victor Osimhen scored the only goal which gave Napoli a 1-0 victory over Bologna in Sunday's Serie A encounter.
Osimhen connected with Hirving Lozano's cross to separate the two teams with his 23rd-minute header.
It was his second goal in the Italian top-flight since he completed a big-money move from Ligue 1 club Lille in the summer.
Shortly after the restart for the second half, Senegal centre-back Kalidou Koulibaly pounced on a rebound after Osimhen attempted an overhead kick, but his strike was ruled out by the VAR because the ball struck the Nigerian striker's hand.
Despite a late challenge from the hosts, Napoli held onto their first-half lead and returned to winning ways after last Sunday's defeat to Sassuolo.
The result stretched the Blues' impressive unbeaten record on the road to three wins this season, excluding the 3-0 forfeit for not honouring their league outing against Juventus last month.
Osimhen was in action for 83 minutes before he was replaced by Andrea Petagna while Koulibaly played the duration but Algeria’s Faouzi Ghoulam did not make the matchday squad.
For Bologna, Gambia striker Musa Barrow featured for the 90 minutes and Nigeria's Kingsley Michael watched on as an unused substitute.
The victory fired Napoli to third on the Serie A table with 14 points after seven games. They have a date with Franck Kessie’s high-flying AC Milan after the international break on November 22.
Osimhen and Koulibaly have been invited to the Nigeria and Senegal squads for their 2021 Africa Cup of Nations qualifiers this week.
Nigeria battle Sierra Leone while the Teranga Lions are scheduled to face Guinea-Bissau.