Sergio Oliveira's free kick in extra-time sent the 10-man Portuguese side through to the next round at the expense of the Serie A holders
Porto overcame Juventus on away goals on Tuesday to progress in a Champions League knockout tie after winning the opening leg for the first time since triumphing in the competition in 2003-04 under Jose Mourinho.
They had earned a clean 2-1 win in the first leg against Juventus but needed to push past self-inflicted damage in the return fixture, breaking their 17-year drought despite allowing their Turin opponents back into the tie with a silly second-half red card.
Sergio Oliveira advanced Porto to the quarter-final with a free kick under the wall in the 115th minute.
What jinx has been broken?
Porto had failed to take advantage of a first-leg knockout victory since 2003-04 against Lyon in the quarter-final, when they put away an opponent featuring future Chelsea signings Michael Essien and Florent Malouda by following a 2-0 win with a second-leg draw.
Mourinho's side that year went on to defeat Monaco in the final.
Porto's experience
Porto's lineup on Tuesday was the second-oldest in their Champions League history (29 years and 16 days), behind only their match with Barcelona in March 2000.
Centre-back Pepe, 38, proved an instrumental part of their triumph, clearing several scoring opportunities.