UEFA.com crunches the numbers to find out which players are predicted for big Matchday 5 totals.
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UEFA.com considers who might be worth choosing for the captaincy, and double points, in the penultimate round of group games.
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Matchday 4 demonstrated the ongoing contributions made by mid and lower-priced midfielders.
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The same strikers continued to deliver, although Real Madrid's Rodrygo pulled in a sensational 18 points.
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Defenders who have the potential to provide attacking returns remain an huge asset, as Achraf Hakimi proved again.
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Clean sheets continued to be hard to come by last time out, although Keylor Navas delivered again.
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Zenit's Group G progress has been stalled by successive defeats as they welcome a Lyon side who would qualify with a win.
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Victory at Benfica on Matchday 1 provided the springboard for Leipzig, who will qualify from Group G with another win.
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LOSC Lille can no longer finish in Group H's top two and need three points against Ajax to avoid coming fourth.
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Valencia sprang a surprise at Chelsea and, with the teams in a three-way head to head with Ajax, will qualify with another win.
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Two heavy defeats have left Crvena zvezda needing to beat a Bayern München side who can secure first place in Group B.
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Tottenham have taken a firm grip on second place in Group B, while Olympiacos have endured a tough campaign.
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Already qualified from Group D, Juventus are looking to clinch first place while Atlético can join them in the last 16.
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Having comfortably won their last three games against Shakhtar, a repeat would guarantee Manchester City's last-16 place.
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Lokomotiv Moskva and Bayer Leverkusen are level on three points in Group D, with the visitors needing a win in Russia.
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Having picked up their first UEFA Champions League point, Atalanta now need a first win as Dinamo Zagreb visit.
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Eliminated Genk will be under new management for the visit of Salzburg, who need a win to maintain their qualifying hopes.
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Slavia have picked up two notable draws, but now need a home victory against Inter to stay in the Group F hunt.
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